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五十一項研究獲撥款

  1. Protective Effect of Chinese Medicine Dwarf Lilyturf Tuber (Maidong) on the Hyperglycemia-induced Cogenital Anomalies (HK$50,000)
    Sponsors: Hong Kong Obstetrical and Gynaecological Trust Fund
    Principal investigator: Prof. Tam Wing-hung (Department of Obstetrics and Gynaecology)
  2. Sensitive and Reproductive Detection of Maternal Blood RNA Markers for Predicting Spontaneous Preterm Birth (HK$50,000)
    Sponsors: Hong Kong Obstetrical and Gynaecological Trust Fund
    Principal investigator: Prof. Stephen Chim (Department of Obstetrics and Gynaecology)
  3. Epigenetic Regulation of Tumor Necrosis Factor-alpha and Lymphotoxin in Human Ovarian Cancer Cells (HK$50,000)
    Sponsors: Hong Kong Obstetrical and Gynaecological Trust Fund
    Principal investigator: Dr. Joseph Kwong (Department of Obstetrics and Gynaecology)
  4. Commissioned Programme on the CUHK Phase I Clinical Trial Centre at the Prince of Wales Hospital (HK$40,000,000)
    Sponsors: Health and Medical Research Fund Commissioned Programme on Phase I1 Clinical Trials Centre
    Principal investigator: Prof. Chan Ka-leung Francis (Faculty of Medicine)
  5. The Effects of Collateral Circulation on the Hemodynamic Flow Status in Intracranial Artery Stenosis as Depicted by the Computational Fluid Dynamics Technique (HK$273,804)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Leung Wai-hong Thomas (Department of Medicine and Therapeutics)
  6. Failure Mode, Strain Localization and Permeability Evolution in Volcanic Rock (HK$22,500)
    Sponsors: PROCORE-France/Hong Kong Joint Research Scheme 2013/2014
    Principal investigator: Prof. Wong Teng-fong (Earth System Science Programme)
  7. Carborane Functionalized π-Conjugated Molecules for Biosensing Materials (HK$90,000)
    Sponsors: PROCORE-France/Hong Kong Joint Research Scheme 2013/2014
    Principal investigator: Prof. Xie Zuowei (Department of Chemistry)
  8. Design, Manufacturing and Swimming Characterization of Scaled-up Prototypes of Helical Microrobots
    Sponsors: PROCORE-France/Hong Kong Joint Research Scheme 2013/2014
    Principal investigator: Dr. Zhang Li (Department of Mechanical and Automation Engineering)
  9. Colloidal Lead Chalcogenide Nanorods for Short-Wavelength Infrared Photodetection (HK$16,200)
    Sponsors: PROCORE-France/Hong Kong Joint Research Scheme 2013/2014
    Principal investigator: Prof. Zhao Ni (Department of Electronic Engineering)
  10. Prenatal Diagnosis of Pathogenic Genomic Imbalance in Fetuses with Increased Nuchal Translucency but Normal Karyotyping Using Microarray-based Comparative Genomic Hybridization (HK$992,212)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Leung Tak-yeung (Department of Obstetrics and Gynaecology)
  11. Limb Salvage with Minimally-invasive Endovascular Therapy for Critical Limb Ischemia in Financially Disadvantaged Patients (HK$2,149,500)
    Sponsors: S. K. Yee Medical Foundation—Donations and Grants for 2013
    Principal investigator: Dr. Yan Ping-yen Bryan (Department of Medicine and Therapeutics)
  12. Longitudinal Course of Insomnia Disorder: Bidirectional Association with Depression and Roles of Biomarkers (HK$999,304)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Zhang Jihui (Department of Psychiatry)
  13. Mobile Self-compassionate Programme for the Promotion of Public Mental Health: Randomised Controlled Trial (HK$876,692)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Mak Wing-sze Winnie (Department of Psychology)
  14. Development of a Label-free Non-PCR Technology for Rapid Infectious Disease Diagnosis (HK$1,986,050)
    Sponsors: Innovation and Technology Fund–Innovation and Technology Support Programme/Guangdong-Hong Kong Technology Cooperation Funding Scheme (Collaborative Research Scheme)
    Principal investigator: Prof. Kong Siu-kai (School of Life Sciences)
  15. Therapeutic Potentials of Stem Cells in Hirschsprung's Disease (HK$999,528)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Chan Wood-yee (School of Biomedical Sciences)
  16. Normal Reference Values of Brachial Artery Flow-mediated Dilation in Healthy Chinese Children and Adolescents (HK$999,500)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Albert Martin Li (Department of Paediatrics)
  17. Relationship of Pst, a High Affinity Phosphate Transporter, Beta-lactam Resistance and Biofilm Formation in Streptococcus Pneumoniae (HK$895,712)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Margaret Ip (Department of Microbiology)
  18. Investigation of Sonodynamic Antifungal Activity of Hypocrellin against Candida Albicans (HK$913,936)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Xu Chuan-shan (School of Chinese Medicine)
  19. Back to the Future: Sense-and Respond Public Transit for Historic Urban Centres (USD$20,000)
    Sponsors: Research Grant from Microsoft Research Asia
    Principal investigator: Prof. Leung May-yee Janny (Department of Systems Engineering and Engineering Management)
  20. Optimal Point of Interest routing in a Urban Environment (USD$20,000)
    Sponsors: Research Grant from Microsoft Research Asia
    Principal investigator: Prof. Cheng Hong (Department of Systems Engineering and Engineering Management)
  21. Urgent versus Early Endoscopy in High Risk Patients with Acute Upper Gastrointestinal Bleeding (HK$829,400)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Lau Yun-wong James (Department of Surgery)
  22. Targeting H2K27 Trimethylation Epigenome for Liver Cancer Prevention (HK$738,206)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Cheng Sze-lok Alfred (School of Biomedical Sciences)
  23. Hepcidin as a Potential Diagnostic Biomarker of Parkinson's Disease (HK$898,240)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Ke Ya (School of Biomedical Sciences)
  24. Investigation of In Vivo and In Vitro Vascular Benefits of Vitamin D in Mouse Models of Obesity and Diabetes (HK$993,920)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Huang Yu (School of Biomedical Sciences)
  25. The Effectiveness of Group Behavioural Activation in the Treatment of Subthreshold Depression in Primary Care in Hong Kong (HK$975,912)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Wong Yeung-shan Samuel (The Jockey Club School of Public Health and Primary Care)
  26. Apathy after Stroke (HK$990,020)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Tang Wai-kwong (Department of Psychiatry)
  27. Vascular Effects of Achieving Minimal Disease Activity (MDA) in Psoriatic Arthritis (PsA)—A 2 Year Prospective Cohort Study (HK$879,422)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Tam Lai-shan (Department of Medicine and Therapeutics)
  28. Enhancing Antibiotics Efficacy by Combinations of Active Ingredients from Traditional Chinese Medicine against Methicillin-resistant Staphylococcus Aureus (HK$999,528)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Fung Kwok-pui (School of Biomedical Sciences)
  29. Photodynamic Therapy Mediated by Natural Products on Methicillin-resistant Staphylococcus Aureus (MRSA)-infected Wound (HK$899,528)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Fung Kwok-pui (School of Biomedical Sciences)
  30. Investigation on FE65 Serine-610 Phosphorylation and Its Functional Implications in Alzheimer's Disease Amyloid Precursor Protein Processing (HK$977,644)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Lau Kwok-fai (School of Life Sciences)
  31. Role of HP1076 in Type IV Secretion Pathway in H.pylori (HK$994,760)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Au Wing-ngor Shannon (School of Life Sciences)
  32. Structure-based Discovery of Inhibitors of Helicobactor Pylori Urease Maturation (HK$994,522)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Wong Kam-bo (School of Life Sciences)
  33. Foreign Language Learning as Potential Treatment for Mild Cognitive Impairment (HK$943,006)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Wong Chun-Man Patrick (Department of Linguistics and Modern Languages)
  34. Risk of Intracerebral Haemorrhage in Patients Taking Oral Anticoagulant for Atrial Fibrillation with Cerebral Microbleeds. A Prospective Study in Warfarin. (IPAAC-Warfarin Study) (HK$997,536)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Soo Oi-yan Yannie (Department of Medicine and Therapeutics)
  35. Evaluation of Nitrous Oxide in the Gas Mixture for Anesthesia: A Randomized Controlled Trial for the Prevention of Chronic Pain after Major Abdominal Surgery (HK$999,752)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Chan Tak-vai Matthew (Department of Anaesthesia and Intensive Care)
  36. Dietary Determinants of Endotoxemia and Nonalcoholic Fatty Liver Disease—A Population Study (HK$914,146)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Wong Wai-sun Vincent (Department of Medicine and Therapeutics)
  37. Promoting Mental Well-being of Pregnant Women with Mindfulness-based Childbirth and Parenting (MBCP): A Randomized Controlled Trial in Hong Kong (HK$1,193,782)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Tsang Wai-kay Katrina (The Jockey Club School of Public Health and Primary Care)
  38. Role and Regulatory Signals of Novel Genes RGS1 and RGS13 in the Homing and Engraftment of Human Hematopoietic Stem/Progenitor Cells for Bone Marrow Immunologic Reconstitution (HK$981,736)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Li Chi-kong (Department of Paediatrics)
  39. Structure-based Drug Design of Anti-influenza Compounds Targeting Influenza Polymerase (HK$998,750)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Shaw Pang-chui (School of Life Sciences)
  40. Novel Antibacterial Actions of Vitamin D and Butyrate in Helicobacter Pylori Infection: Involvement of Cathelicidin and Autophagy (HK$998,220)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Cho Chi-hin (School of Biomedical Sciences)
  41. Modulation of Host Cell CpG Methylation Machinery by EBV Infection in Carcinomas and its Clinical Application (HK$890,000)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Tao Qian (Department of Clinical Oncology)
  42. Development and Pilot Study of Monoclonal Antibodies for Rapid Screening of HLA-B* 15:02 to Enable Safer Use of Carbamazepine (HK$675,158)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Kwan Kwok-leung Patrick (Department of Medicine and Therapeutics)
  43. The Health Effects of Traffic-related Air Pollution in Hong Kong School Children (HK$979,705)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Lao Xiangqian (The Jockey Club School of Public Health and Primary Care)
  44. Ictal Intracranial Electroencephalography Using Wavelet Analysis of High-frequency Oscillations in Chinese Patients with Refractory Epilepsy (HK$965,000)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Leung Howan (Department of Medicine and Therapeutics)
  45. A Randomized Controlled Trial Evaluating Efficacy of Promoting Home-based HIV Testing with Online Counseling on Increasing HIV Testing among Men who Have Sex with Men (HK$999,990)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Lau Tak-fai Joseph (The Jockey Club School of Public Health and Primary Care)
  46. Preclinical Study of Neuroprotective Effect of Gastrodia-Uncaria Water Extract and Interaction with Tissue Plasminogen Activator Treatment on Embolus Induced Cerebral Ischemia (HK$999,608)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Chan Chun-wai (School of Chinese Medicine)
  47. Self-determination Theory-based Exercise Programmes for the Enhancement of Exercise Adherence and Well-being among People with Depression: Randomised Controlled Trial (HK$715,941)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Mak Wing-sze Winnie (Department of Psychology)
  48. Investigation of the Combined Use of Andrographis Paniculata and Chemotherapeutics in the Treatment of Metastatic Esophageal Cancer—A Clinical Study (HK$999,608)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Chiu Wai-yan Philip (Department of Surgery)
  49. Integrating the Humanities across National Boundaries (US$70,000)
    Sponsors: Andrew W. Mellon Foundation
    Principal investigator: Prof. Hsiung Ping-chen (Research Institute for the Humanities)
  50. A Randomized Clinical Trial to Compare a Strategy Utilizing Genetic Testing and Personalized Risk Counselling with Standard Care on Patient Empowerment, Risk Factors Control and the Risk of Diabetic Complications (HK$996,932)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Prof. Ma Ching-wan Ronald (Department of Medicine and Therapeutics)
  51. Neutralizing Antibodies to Interferon-beta Therapy in Chinese Patients with Relapsing and Remitting Multiple Sclerosis: A Pilot Study (HK$997,260)
    Sponsors: Health and Medical Research Fund
    Principal investigator: Dr. Lau Yuk-lun Alexander (Department of Medicine and Therapeutics)

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