-
R&D of a Novel Bone Targeting Delivery System Carrying Bone-forming Phytomolecule Icaritin for Prevention of Osteonecrosis (HK$997,540)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Qin Ling (Department of Orthopaedics and Traumatology) -
A Randomized Controlled Trial Comparing the Efficacy and Safety between Pattern Laser Trabeculoplasty and Selective Laser Trabeculoplasty (HK$990,518)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Leung Kai-shun Christopher (Department of Ophthalmology and Visual Sciences) -
A Study on the Relationship between Maternal Iodine and Thyroid Status, and Autoimmune Thyroid Disease, on Placental Thyroid and Iodide Transport System in Chinese Women (HK$998,976)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lao Tzu-hsi Terence (Department of Obstetrics and Gynaecology) -
Nudges to Influence Influenza Vaccine Uptake in Children: A Randomized Controlled Trial (HK$979,801)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Nelson Edmund Anthony (Department of Paediatrics) -
Development of System Using Routine Surveillance Data to Estimate Influenza Vaccine Effectiveness for Hospitalized Hong Kong Children (HK$995,452.5)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Nelson Edmund Anthony (Department of Paediatrics) -
Mechanism-guided Design of Tradition Chinese Herbal Formula (Fok Fong) for Prevention and Treatment of Metabolic Syndrome (HK$932,408)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lee Sau-tuen Susanna (School of Life Sciences) -
Investigation on Ataxia Disorder by Using a Novel Genetically-modified Mouse Model (HK$999,880)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Kwan Kin-ming (School of Life Sciences) -
Illuminating the Functional Abnormalities of Brain Networks Underlying Social Communication and Repetitive Behaviours in Autism Spectrum Disorder (ASD): Implication on a Neurobiological Treatment of Neurofeedback (HK$754,538)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lai Yee-ching Kelly (Department of Psychiatry) -
The Role of Huperzine A in Treatment of β Amyloid Associated-neuropathology in a Mouse Model of Alzheimer's Disease (HK$722,276)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Yuan Qiuju (School of Chinese Medicine) -
Synergism between Tamoxifen and Marmorin, a Ribosome Inactivating Protein from an Edible Medicinal Mushroom, on Breast Cancer in Vitro and in Vivo: A Mechanistic Study (HK$999,128)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Ng Tzi-bun (School of Biomedical Sciences) -
Psychopathology, Executive Dysfunction and Role Impairment in Chinese Young Adults with a Previous Clinical Diagnosis of Childhood Attention-deficit/Hyperactivity Disorder in Hong Kong (HK$504,020)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Mak Dun-ping Arthur (Department of Psychiatry) -
Biological Crystal Subunit Vaccines for Mycobacterial Diseases (HK$1,000,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Michael Chan (School of Life Sciences) -
Volumetric Bone Mineral Density and Bone Microarchitecture: A New Population-based Reference Study with High Resolution Peripheral Quantitative Computer Tomography (HK$996,216)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Qin Ling (Department of Orthopaedics and Traumatology) -
An Investigation into the Therapeutic Potential of Human Fetal Pancreatic Progenitor Cells for Islet Transplantation (HK$995,128)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Leung Po-sing (School of Biomedical Sciences) -
Molecular Screening for Community-based Cephalosporin-resistant Neisseria Gonorrhoeae in Key Populations in Hong Kong (HK$999,836)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Pui-chung Denise (Stanley Ho Centre for Emerging Infectious Diseases) -
Electroacupuncture plus Standard Care for Managing Refractory Functional Dyspepsia: Pragmatic Randomized Trial with Economic Evaluation (HK$1,000,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chung Chi-ho Vincent (The Jockey Club School of Public Health and Primary Care) -
Meteorological Risk Factors for Hospital Admissions among Patients with Diabetes Mellitus in Hong Kong (HK$423,600)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. William B. Goggins (The Jockey Club School of Public Health and Primary Care) -
The Concordance of KRAS, BRAF, PIK3CA, and PTEN Status between Primary Tumors and Corresponding Metastases in Patients with Colorectal Cancer: A Systematic Review and Meta-analysis (HK$356,664)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Mao Chen (The Jockey Club School of Public Health and Primary Care) -
Improving Elderly Health Care Voucher Scheme to Incentivise Primary Care in Hong Kong: How has Health Service Utilization Changed (HK$889,732)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Liu Su (The Jockey Club School of Public Health and Primary Care) -
Evaluation of the Adoption of the Reference Framework for Hypertension in Primary Care: A Mixed Qualitative and Quantitative Study (HK$989,733)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Wong Chi-sang Martin (The Jockey Club School of Public Health and Primary Care) -
Structure-based Screening for G6PD Stabilizers to Overcome Primaquine-induced Hemolysis in Anti-malaria Treatment (HK$972,276)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Au Wing-ngor Shannon (School of Life Sciences) -
To Evaluate the Effect of Salvianolic Acid B on Bone Fusion in comparison with Autograft in a Rat Spinal Fusion Model (HK$722,432)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Lee Yuk-wai Wayne (Department of Orthopaedics and Traumatology) -
The Development of Mechanically Robust Hyaluronic Acid Hydrogels for Joint Cartilage Repair (HK$999,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Bian Liming (Department of Mechanical and Automation Engineering) -
Targeted Drug Discovery for Alzheimer's Disease (HK$727,564)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Man-lok Andrew (School of Biomedical Sciences) -
Internet-based Mindfulness and Rumination-focused Cognitive Behavioural Therapy as Selective Prevention of Anxiety and Depression: A Randomized Controlled Trial (HK$999,692)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Mak Wing-sze Winnie (Department of Psychology) -
A Randomized Controlled Trial Evaluating Efficacy of a Psychological Intervention Based on Commonsense Model in Improving Mental Health and Self-care among Type-2 Diabetes Mellitus Patients (HK$999,003.75)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Mo Kit-han Phoenix (The Jockey Club School of Public Health and Primary Care) -
Rapid Sample-to-answer Smart Lab-on-a-disc Pharmacogenetic Testing Device for Personalized Medicine (HK$988,328)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Ho Ho-pui Aaron (Department of Electronic Engineering) -
A Randomized Controlled Trial Evaluating Efficacy of an Intervention Which Enhances Social Support and Positive Affect through Online Social Networking in Smoking Cessations (HK$999,904)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lau Tak-fai Joseph (The Jockey Club School of Public Health and Primary Care) -
Dysregulation of miR223 and miR431 Expression in Intestinal Tissues of Preterm Infants with Necrotising Enterocolitis: Roles in Altering Enterocyte Gene Expressions and Functions (HK$758,902)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Ng Pak-cheung (Department of Paediatrics) -
Behavioural Dysexecutive Syndrome after Stroke (HK$1,250,012)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tang Wai-kwong (Department of Psychiatry) -
A Randomized Controlled Trial Examining the Effectiveness of a Lifestyle Intervention in Reducing Gestational Diabetes Mellitus in High Risk Chinese Pregnant Women in Hong Kong (HK$989,445.95)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Suk-mei Ruth (Department of Medicine and Therapeutics) -
Left Ventricular Mass and Clinical Characteristics of Persistent Masked Hypertension in Hong Kong Youth—A Community Cohort Study (HK$995,878)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Yam Man-ching (Department of Paediatrics) -
Relationship between Chronic Inflammation and Vitamin D Level to Prevalent and Incident Frailty in Older Adults (HK$996,108)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Lee Shun-wah Jenny (Department of Medicine and Therapeutics) -
Treatment of Parkinsonian Symptoms via Stochastic Stimulation of the Motor Cortex: A Proof-of-principle Study (HK$999,378.5)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Yung Wing-ho (School of Biomedical Sciences) -
Immunotherapy and Modulatory Mechanisms of Hypoallergen DNA Vaccines for Shellfish Allergy (HK$999,657.6)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chu Ka-hou (School of Life Sciences) -
Sulfur Amino Acids as Risk Factors for Obesity and Related Morbidities in Older Chinese People (HK$638,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Kwok Chi-yui Timothy (Department of Medicine and Therapeutics) -
Cellular Mechanisms Underlying the Benefits of Danshen-derived Salvianolic Acid B against Vascular Inflammation and Dysfunction in Diabetes (HK$999,916)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Huang Yu (School of Biomedical Sciences) -
An Observational Follow Up Study on Pelvic Floor Disorders Related to Three Years after Delivery (HK$221,934)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Chan Shing-chee Symphorosa (Department of Obstetrics and Gynaecology) -
A Prospective Observational Study to Validate the Reliability of the Early Pregnancy Viability Scoring System (HK$274,822)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Wan Yee-ki Osanna (Department of Obstetrics and Gynaecology) -
Impact of the Chinese Herbal Medicines on the Combination Therapy with Clopidogrel and Aspirin: Pharmacokinetics and Pharmacodynamics Outcomes and Related Mechanisms in Rats (HK$909,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Zuo Zhong (School of Pharmacy) -
The Effects of an Activity-based Lifestyle Intervention on Moderate Sleep Complaints among Older Adutls: A Sequential Mixed Method Study (HK$818,519.11)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Yu Sau-fung Doris (The Nethersole School of Nursing) -
An Investigation of Amyloid Precursor Protein in Triple Negative Breast Cancers and its Potential Clinical Value (HK$997,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Tse Man-kit Gary (Department of Anatomical and Cellular Pathology) -
A Randomized Controlled Trial of Combined Physical Exercise-working Memory Training on Slowing Down Cognitive Decline in Elders with Mild Clinical Alzheimer's Disease (HK$956,187)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lam Chiu-wa Linda (Department of Psychiatry) -
Tetramethylpyrazine (TMP) as a Novel HIF Activator for Promoting Angiogenesis and Osteogenesis during Skeletal Regeneration (HK$1,000,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wan Chao (School of Biomedical Sciences) -
Investigation of the Antitussive Effects of a Folk Medicine, Cardiocrinum Seeds (HK$995,128)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Shaw Pang-chui (School of Life Sciences) -
Randomized Sham-controlled Trial of Augmentative Neuro-navigated Right-dorsolateral Prefrontal Cortex Low-frequency Repetitive Transcranial Magnetic Stimulation for Antidepressant Non-responding Bipolar Depression (HK$977,730)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Mak Dun-ping Arthur (Department of Psychiatry) -
A Functional Study of Nuclear Receptor LRH-1 and its Targeting in Prostate Cancer (HK$913,304)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Leung Franky (School of Biomedical Sciences) -
Mast Cells Activities and Osteoporosis—A Novel Research Platform for the Study of Interaction of Herbal and Western Anti-Osteoporosis Agents in Human (HK$998,276)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lau Hang-yung Alaster (School of Biomedical Sciences) -
A Pragmatic Randomized Controlled Trial Comparing an Integrated Electroacupuncture Protocol vs Sham-control in Chinese Adults with Generalized Anxiety Disorder and Diarrhea-predominant Irritable Bowel Syndrome (HK$749,630.8)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Mak Dun-ping Arthur (Department of Psychiatry) -
Investigation of the Effects of Gastrodiae Rhizoma—Containing Herbal Formula (DCXF) in Traumatic Brain Injury Rate Model (HK$957,912)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Ko Chun-hay (Institute of Chinese Medicine) -
A Randomized Controlled Trial on Perioperative Elderly Patients Undergoing Colorectal Cancer Surgery with Enhanced Geriatric Input (HK$528,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Mak Wing-chung Tony (Department of Surgery) -
Delineation of Therapeutic Potential and the Causal Relationship between Vitamin D and Helicobacter Pylori (HP) Infection and Gastritis (HK$1,000,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wu Che-yuen Justin (Hong Kong Institute of Integrative Medicine) -
Evaluation of the Effectiveness of Tai Chi versus Brisk Walking in Reducing Cardiovascular Risk Factors: A Randomized Controlled Trial (HK$863,760.5)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Wai-kiu Aileen (The Nethersole School of Nursing) -
Exploring the Functional Roles of Stromal Leukotrienes in Cancer Development and Treatment (HK$846,408)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Cheung Wing-tai (School of Biomedical Sciences) -
Adjunctive Light Treatment in Major Depressive Disorder among Evening Chronotype—A Randomized Controlled Trial (HK$839,980)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wing Yun-kwok (Department of Psychiatry) -
The Translation of Gastrodia Elata from Laboratory to Clinical Practice: The Study and Treatment of Epilepsy as a Window to Neuroscience (HK$847,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Leung Howan (Department of Medicine and Therapeutics) -
A Randomized Controlled Trial of a New Screening Strategy for Varices Based on Liver and Spleen Stiffness Measurement (LSSM) in Cirrhotic Patients (HK$895,785)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Wong Lai-hung Grace (Department of Medicine and Therapeutics) -
Effect of Short Course Pulmonary Rehabilitation on the Activity and Frequency of Exacerbations of Patients with Chronic Obstructive Pulmonary Disease (COPD) (HK$789,020)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Ko Wai-san Fanny (Department of Medicine and Therapeutics) -
Genetic Predictors of Perioperative Myocardial Injury—The GeneVISION Study (HK$999,860.5)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tony Gin (Department of Anaesthesia and Intensive Care) -
Familial Aggregation and Biomarkers in REM Sleep Behaviour Disorder: A Case-control Family Study (HK$994,423.5)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Zhang Jihui (Department of Psychiatry) -
Using a Novel and Noninvasive Cerebral Augmentation Index as Evaluated by External Counterpulsation to Predict Long-term Clinical Outcome after Acute Ischemic Stroke (HK$673,304)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wong Ka-sing Lawrence (Department of Medicine and Therapeutics) -
Non-invasive Assessment of Cardiovascular Reserve in Patients with Systemic Autoimmune Diseases (HK$833,148)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Shang Qing (Department of Medicine and Therapeutics) -
Neural Responses to Pitch in Cantonese-speaking Children with Autism Spectrum Disorders (HK$765,304.8)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wong Chun-man Patrick (Department of Linguistics and Modern Languages) -
Effects of Early Life Adversity on the Development of Enteric Neurons (HK$956,432)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Chan Wood-yee (School of Biomedical Sciences) -
Genetic Susceptibility of Hong Kong Ethnic Chinese to Severe Influenza and RSV Infections (HK$999,823)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lee Lai-shun Nelson (Department of Medicine and Therapeutics) -
A Study of Efficacy on the Combination Use of Anti-osteoporosis Drug with Topical Chinese Herbal Paste on Facilitation of Fracture Healing (HK$927,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Leung Ping-chung (Institute of Chinese Medicine) -
Is it Safe to Use Estrogenic Chinese Herbal Medicines in Breast Cancer Patients?—A Preclinical Evaluation (HK$992,288)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Lau Bik-san Clara (Institute of Chinese Medicine) -
Comparison of Serum Thromboxane B2 and Platelet Function Testing with the Multiple® Device as Measures of Aspirin Resistance in Hong Kong Chinese Patients with Increased Cardiovascular Risk with Stable Coronary Heart Disease or Peripheral Artery Disease (HK$641,474)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Brian Tomlinson (Department of Medicine and Therapeutics) -
Prevention of Vasovagal Reactions in Blood Donors: A Randomized Double-blinded Controlled Comparison of Efficacy and Haemodynamic Effects of Oral Prehydration Fluids (HK$999,042)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Khaw Kim-sun (Department of Anaesthesia and Intensive Care) -
Identification of Alterations in Host Genome Methylation Driven by the Human Immunodeficiency Virus Type 1 (HK$999,408)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tsui Kwok-wing (School of Biomedical Sciences) -
Association Study of Susceptibility Genes in Wnt Signalling Pathway with Attempted Suicide (HK$940,368)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Waye Miu-yee (School of Biomedical Sciences) -
The Anti-apoptotic and Anti-proliferative Role of FHL2 Mediated by p53, IL6 and STAT3 (HK$999,408)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tsui Kwok-wing (School of Biomedical Sciences) -
Peak Oxygen Uptake in Healthy Chinese Children and Adolescents by Age, Sex and Maturation (HK$999,887.25)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Albert Martin Li (Department of Paediatrics) -
Role of Platelet-T Cell Interactions in Pathogenesis of Multiple Sclerosis (MS) and Neuromyelitis Optica (NMO) (HK$785,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Eugene Ponomarev (School of Biomedical Sciences) -
Molecular Stratification of Lower Grade Gliomas in Routine Practice in Hong Kong (HK$728,624)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Ng Ho-keung (Department of Anatomical and Cellular Pathology) -
Genetic Studies of Tuberculosis: In-depth Study of Recently GWAS Identified Loci in Chinese Patients (HK$987,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tang Leung-sang Nelson (Department of Chemical Pathology) -
Therapeutic Treatment against Ocular Inflammation by Green Tea Extract and Catechins in Experimental Uveitis (HK$952,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Pang Chi-pui (Department of Ophthalmology and Visual Sciences) -
Biomedical Effects of Green Tea Extracts on Experimental Age-related Macular Degeneration (HK$997,414)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Ng Tsz-kin (Department of Ophthalmology and Visual Sciences) -
Novel Treatment of Intermittent Claudication in Patients with Peripheral Arterial Disease Using Danshen Gegen (D&G) Capsule (HK$999,800)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Yan Ping-yen Bryan (Department of Medicine and Therapeutics) -
Gestational Temporal Behaviour and Cut-off Values of Soluble fms-Like Tyrosine Kinase-1, Placental Growth Factor and its Ratio as a Diagnostic Test for Pre-eclampsia in Chinese (HK$411,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Cheng Kwun-yue Yvonne (Department of Obstetrics and Gynaecology) -
Evaluation of Riboflavin/Ultraviolet-mediated Collagen Crosslinking with Photoactivated Riboflavin (Photoactivated Chromophore for Keratitis [PACK]-CXL) as Adjunctive Treatment for Infectious Keratitis: A Randomized Controlled Trial (HK$402,448.2)
Sponsors: Health and Medical Research Fund
Principal investigator: Dr. Vishal Jhanji (Department of Ophthalmology and Visual Sciences) -
A Randomized Controlled Trial of Rapid Movement Therapy with Real-time Feedback to Improve Balance Recovery for Fall Prevention after Stroke (HK$858,000)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Tong Kai-yu Raymond (Department of Electronic Engineering) -
Plasma microRNAs as Prognostic Biomarkers for Localized Prostate Cancer (HK$631,408)
Sponsors: Health and Medical Research Fund
Principal investigator: Prof. Wang Feng (The Jockey Club School of Public Health and Primary Care)