Newsletter No. 45

No.45 August 1993 CUHK Newsletter Project Title CUHK Investigator(s) Amount Approved (HK$ million) The study of cerebral perfusion and oxygenation by near-infrared spectroscopy (NIRS) in head-injured patients Dr. P.K.K Au Yeung Dr. W.S. Poon Prof. I E. Oh 0.432 Developmen t of an enzyme-linked immunosorben t assay (ELISA) using a novel monoclona l antibody against 6 ß -hydroxycortisol to detect enzyme induction in man Dr. J.H.K Yeung 0.221 Production of autoantigens by gene fusion and peptide synthesis for use in the immunodiagnosi s of autoimmune disease Dr. P.L. Lim Dr. Y.L . Chui 0.551 The immunomodulator y and antitumour properties of secretory products from cultured mushroom mycelia Dr. W.K. Liu Dr. I B. Ng Dr. V.E.C Ooi Prof. S.T. Chang 0.741 Genotyping of the low-densit y receptor defects in familia hypercholesterolaemi a in Hong Kong Prof. J.R.L Masarei Dr. C.P. Pang Dr. B. Tomlinso Dr. J.E. Sanderson 0.348 Studies on the renal sodium dopamine relationshi p and the effects of sodium loading on blood pressure, natriuretic and hormonal responses in normotensive Chines with or without a family history of hypertensio Dr. T.Y.K Chan Dr. B. Tomlinso Dr. J.C.N Chan Prof. J.A.J.H Critchley 0.841 An investigation of interactions between natriuretic peptides, vasoconstricto r hormones and growth factors in cultured glial cells Dr. V.T.F Yeung Dr. C.S. Cockram Dr. D.S.C Tsang 0.756 Genetic changes in chromosome 3 in oncogenesi s and pathogenesi s of nasopharyngea l carcinoma (NPC) Dr. D.W.S Poon Huang Prof. J.C.K Le Dr. S.F. Leung 0.56 A territory-wide strategy for the preventio of occupationa l hazards arising from chemical substances Dr. U.S. Yu Dr. T.W.Wong 0.401 Angiogenesi s inhibitors: isolation, purification and characterization of a potential anti-cancer therapeuti c from shark cartilage. Prof. K.P. Wong 0.406 Physical Sciences 3, 4-Bis (trimethylsilyl) - and 3,4-Bis (trialkylstannyl)-furans , pyrroles and thiophenes : versatile building blocks of 3,4-disubstitute d five-membered heterocycles Dr. N.C. Wong 0.619 Physics of random nonlinear composite Dr. K.W. Yu Dr. P.M. Hui 0.52 Studies of structure, dynamics and kinetics of polyelectrolyt e gels Dr. C. Wu 0.546 Structural modification of highly undercooled semiconductor s and metals Dr. H.W. Kui 0.537 Correlated squeezed-stat e approach for a dissipative two-state system Dr. C.F. Lo 0.26 The role of electronic factor on the stereoselectivit y of organic reactions: a molecular design and artificial intelligent approach Dr. H.F. Chow Dr. L.W. Chan 0.51 Application of polycrystalline 59Co NMR to the study of synthetic biopolymer 一 probing the effect of outer-sphere interactions of diamagneti c Co (III) -ammine complexes on the secondary structure of nucleic acid Dr. S.C.F Au Yeung 0.672 Simultaneous quantitative analysis of natural sugars and amino acids in dilute aqueous solution by WATR-CPMG 1H NMR spectroscopy -application in medical , environmenta l and biotechnology research Dr. S.C.F Au Yeung 0.328 Synthetic and structural studies of metallacycles Dr. K.W.P Leung 0.331 Transition metal carben complexes in organic synthesis Dr. K.S. Chan 0.412 Synthesis and structural studies of metal complexes containing polyfunctiona l carboxylate-lik e ligands Prof. T.C.W. Mak 1.0 Expanding the uses of a new version of the Ramberg-Backlun d reaction in organic synthesis Dr. T.L. Chan 0.574 7