Newsletter No. 115

4 No. 115 4th November 1997 CUHK Newsletter 研究題目 Project Title 研究員 CUHK Investigator(s) 獲撥款項(港元) Amount Approved (HK$) (生物及醫學 Biology and Medicine cont'd ) •生長抑制基因 PML 在肝癌及鼻咽癌的改 變 Alterations of the Growth and Transformation-suppressor PML in Hepatocellular Carcinoma and Nasopharyngeal Carcinoma 梁承暉教授 Prof. Sing-fai Leung 陳若翰教授 Prof. John Y.H. Chan 陳德章教授 Prof. Anthony T.C. Chan 劉宗石教授 Prof. Choong-tsek Liew 莊立信教授 Prof. Philip J. Johnson 686,880 • 血 淸醣蛋白同型異體之探測、提純及檢 定:作爲癌症診斷與分類的標誌 Detection, Purification and Identification of Isoforms of Serum Glycoproteins: Use as Diagnostic and Dedifferentiation Markers in Cancer 陳德章教授 Prof. Anthony T.C. Chan 莊立信教授 Prof. Philip J. Johnson Dr. T. Lane 楊孟思教授 Prof. N.M. Hjelm 何宗信博士 Dr. Chung-shun Ho 638,280 •以探測及顯示循環肝癌細胞特質來預測肝 癌復發機會及監察其治療進展 Detection and Characterization of Circulating Hepatocellular (HCC) Cells for Predicting HCC Metastasis and Monitoring Treatment of HCC Patients 楊明明教授 Prof. Winnie Yeo 莊立信教授 Prof. Philip J. Johnson 梁惠棠教授 Prof. Thomas W.T. Leung 劉允怡教授 Prof. Joseph W.Y. Lau 500,000 •內鏡超聲波與磁力共振推測門脈高壓出血 的作用 The Use of Endosonography and MR Angiography in Predicting the Risk of Variceal Bleeding in Portal Hypertension 沈祖堯教授 Prof. Joseph J.Y. Sung 陳宇亮教授 Prof. Yu-leung Chan 鍾尙志教授 Prof. Sydney S.C. Chung 林慧雯教授 Prof. Wynnie W.M. Lam 470,880 •血管內皮生長素受體在睪九巨噬細胞之驗 證及機能的硏究 Identification and Functional Studies of VEGF Receptors in Rat Testicular Macrophages 區澤樑教授 Prof. Chak-leung Au 669,600 •骨與骨和骨與肌腱癒合的生物力學和組 織學對比硏究——山羊模型 A Comparative Study of the Mechanical and Histological Properties of Bone to Bone Union and Bone to Tendon Healing — A Goat Model 王韻娜教授 Prof. M. Wan-nar Wong 秦嶺教授 Prof. Ling Qin 梁國穗教授 Prof. Kwok-sui Leung 張元亭教授 Prof. Yuan-ting Zhang 740,880 • BMP 復合羥基磷灰石用於不去除皮質骨 之脊柱後路融合術 Application of Bone Morphogenetic Protein- Hydroxyapatite Composite Implant in Un- decorticated Posterior Spinal Fusion 鄭振耀教授 Prof. Jack C.Y. Cheng 郭霞博士 Dr. Xia Guo 李廣文博士 Dr. Simon K.M. Lee 643,680 •胎兒與孕婦之有核細胞交流 Trafficking of Nucleated Cells between Fetus and Mother 楊孟思教授 Prof. N.M. Hjelm 盧煜明教授 Prof. Dennis Y.M. Lo 張明仁教授 Prof. Allan M.Z. Chang 686,880 研究題目 Project Title 研究員 CUHK Investigator(s) 獲撥款項(港元) Amount Approved (HK$) •神經腫瘤遺傳分子硏究 Studies on the Molecular Genetics of CNS Tumours 吳浩強教授 Prof. Ho-keung Ng 黃潘慧仙教授 Prof. Dolly W.S.P. Huang 林映波博士 Dr. Paula Y.P. Lam 羅國煒先生 Mr. Kwok-wai Lo 潘偉生教授 Prof. Wai-seng Poon 686,880 •有關新基因 BRE 的功能硏究 Functional Analysis of a New Gene (BRE) Responsive to DNA Damage and Retinoic Acid, and Its Interactions with the TNF Receptor 陳若翰教授 Prof. John Y.H. Chan 686,880 ‧對患上中腦動脈狹窄而無病徵者的前瞻 性硏究 A Prospective Study of Asymptomatic Patients with Middle Cerebral Artery Stenosis 黃家星教授 Prof. Lawrence K.S. Wong 林慧雯教授 Prof. Wynnie W.M. Lam 楊鐸輝教授 Prof. Vincent T.F. Yeung 陳宇亮教授 Prof. Yu-leung Chan 祁理治教授 Prof. Richard L.C. Kay 481,380 ‧AnEpidemiological Study of Narcolepsy in Hong Kong Chinese 榮潤國教授 Prof. Yun-kwok Wing 陳佳鼐教授 Prof. Char-nie Chen 何國華先生 Mr. Crover K.W. Ho 梁業成先生 Mr. Tony Y.S. Leung 李錦滔醫生 Dr. Philip K.T. Li 751,450 • A Comparative Investigation of Telomerase Activity in Human Liver with Hepatocellular Carcinoma, Chronic Viral B Hepatitis, Cirrhosis, and Normal Liver 劉宗石教授 Prof. Choong-tsek Liew 劉允怡教授 Prof. Joseph Y.W. Lau 李川軍教授 Prof. Joseph C.K. Lee 718,680 •香港華人二型糖尿病形成的環境因素及 基因硏究 Phenotypic and Genotypic Characterization of NIDDM and Their Interactions with Environmental Factors 陳重娥教授 Prof. Juliana C.N. Chan 鄭鍾淑嫻教授 Prof. Shuk-han C. Cheng 楊鐸輝教授 Prof. Vincent T.F. Yeung 周振中博士 Dr. Francis C.C. Chow 郭克倫教授 Prof. Clive S. Cockram 郭志良教授 Prof. Julian A.J.H. Critchley 686,880 •具抗愛滋病毒活性的天然產物 Natural Products with Anti-human Immunodeficiency Virus Activity 吳子斌教授 Prof. Tzi-bun Ng 楊顯榮教授 Prof. Hin-wing Yeung 溫志昌教授 Prof. David C.C. Wan 方永平教授 Prof. Wing-ping Fong 786,480 •妊娠糖尿病對胚胎發育影響的分子生物 基礎,以及母體糖尿狀況與基因及環境 因素的相互關係之硏究 A Study of the Molecular Basis of Diabetic Embryopathy and Interaction of Maternal Diabetic Milieu with Genetic or Environmental Factors 沈秀媛教授 Prof. Alisa S.W. Shum 686,880 物理科學 Physical Sciences 研究題目 Project Title 研究員 CUHK Investigator(s) 獲撥款項(港元) Amount Approved (HK$) •手性呋喃硼酸酯在有機合成之應用 The Use of Chiral Furanboronates in Organic Synthesis 黃乃正教授 Prof. Henry N.C. Wong 496,000 •新型甜菜碱配位體及其金屬化合物的合 成與結構硏究 Synthesis and Structural Studies of New Betaine Ligands and Their Metal Complexes 麥松威教授 Prof. Thomas C.W. Mak 476,000 •複合分形結構及自相似 Multifractal Structure and Self-similarity 劉家成教授 Prof. Ka-sing Lau 396,000 •利用激光光散射硏究可生物降解的高分子 Laser Light-scattering Studies on Biodegradable Polymers 吳奇教授 Prof. Chi Wu 456,000 •低能電子與三五族半導體之相互作用 Interaction of Low Energy Ions and III-V Semiconductors 郭偉民教授 Prof. Raymund W.M. Kwok 劉煥明教授 Prof. Leo W.M. Lau 446,000 •有機稀士碳硼烷配合物的合成、結構及反 應硏究 Lanthanacarborane Complexes: Synthesis, Structure and Reactivity 謝作偉教授 Prof. Zuo-wei Xie 540,000 •抗腫瘤藥物 Simalikalactone D 和 Quassimarin 的立體專一性全合成 Enantiospecific Total Syntheses of Anticancer Agents Simalikalactone D and Quassimarin 成公明教授 Prof. Tony K.M. Shing 639,000 •以石墨爐原子吸收光譜直接測定大氣微 粒物質中的重金屬 Development of New Methods for the Direct Determination of Heavy Metals in Atmospheric Particulate Matter by Graphite Furnace Atomic Absorption Spectrometry 余濟美教授 Prof. Jimmy C.M. Yu 546,000 •相對論天文物理——中子星之碰撞 General Relativistic Astrophysics: Coalescences of Neutron Star Binaries 朱明中教授 Prof. Ming -Chung Chu 梁培燈教授 Prof. Pui-tang Leung 396,000 研究題目 Project Title 研究員 CUHK Investigator(s) 獲撥款項(港元) Amount Approved (HK$) •以第一原理分子動力力學硏究分子和能量 材料熱分解的反應機制 First Principle Molecular Dynamics Study on the Reaction Mechanisms of Thermal Dissociation for Molecules and Energetic Materials 劉志鋒教授 Prof. Zhi-feng Liu 426,000 • Hubbard 模式之模擬 Quantum Monte Carlo Simulations of Three-band Hubbard Model 林海青教授 Prof. Hai-qing Lin 446,000 •交通流問題中的統計物理方法 Vehicular Traffic Flow Problems: Statistical Physics Approaches 許伯銘教授 Prof. Pak-ming Hui 396,000 •氧在巨磁阻材料內的作用 Oxygen Effects in Colossal Magnetoresistance Materials 黃康權教授 Prof. Hong-kuen Wong 446,000 •有關環、半群及一般古典群上的一般 Morita 等價理論 General Theory of Morita Equivalence for Rings, Semigroups, General Classical Groups and Their Applications 岑嘉評教授 Prof. Kar-ping Shum 396,000 •調和映射與流形結構 Harmonic Maps and Structures of Manifolds 溫有恆教授 Prof. Tom Y.H. Wan 396,000 •區域幾何與拓撲對非線性方程解的影響 On the Effect of Domain Geometry and Topology in Nonlinear Elliptic Equations 魏軍城教授 Prof. Jun-cheng Wei 396,000 •寡聚聯酴酚之合成及性質硏究 Optically Active, Axially Chiral, Bi-naphthol- based Conjugated Oligomers: Synthesis, Characterization, Properties and Applications 周克勳教授 Prof. Hak-fun Chow 496,000 •積分方程之快速選代法 Fast Iterative Methods for Integral Equations 陳漢夫教授 Prof. Raymond H.F. Chan 486,000

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