47 Research Projects and Events Receive Grants

Clinical Profile of Lower Urinary Tract Changes and Urinary Marker Measurements in Young Adults Using Ketamine (HK$294,400)
Sponsor: Beat Drugs Fund
Principal investigator: Prof. Yip Kam-hung Sidney, Department of Surgery

The Detrimental Effects of Long-term Ketamine with Alcohol Abuses in Mice and Its Use in an Educational Programme (HK$1,719,287)
Sponsor: Beat Drugs Fund
Principal investigator: Prof. Yew Tai-wai David, School of Biomedical Sciences

A Multi-centre Study to Investigate the Prevalence and Factors Associated with Depression in Chinese Patients with Type 2 Diabetes (€150,000)
Sponsor: European Foundation for the Study of Diabetes
Principal investigator: Prof. Chan Chung-ngor Juliana, Hong Kong Institute of Diabetes and Obesity

Mining User Travel Paths for Personalized Point-of-Interest Recommendation (US$70,000)
Sponsor: Google Focused Grant Project ‘Mobile 2014’
Principal investigator: Prof. Lyu Rung-tsong Michael, Department of Computer Science and Engineering

A Mechanistic Study of Scutellaria Baicalensis Georgi (Huangqin) and Rosiglitazone Co-administration on the Treatment of Type 2 Diabetes Mellitus (HK$988,728)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Kwan Yiu-wa, School of Biomedical Sciences

A Randomized Controlled Trial of Intravitreal Bevacizumab Monotherapy Versus Triple Therapy with Half Fluence Verteporfin Photodynamic Therapy, Intravitreal Bevacizumab and Triamcinolone Acetonide for the Treatment of Neovascular Age-related Macular Degeneration (HK$690,996)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Lam Shun-chiu Dennis, Department of Ophthalmology and Visual Sciences

A Study on the Pharmacological Interactions between a Chinese Herbal Formula ELP and Standard Anti-resorptive Drugs Used to Counteract Osteoporosis (HK$981,728)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Han Quan-bin, Institute of Chinese Medicine

Adverse Events and Poisonings from Over-the-counter Traditional Chinese Medicine: A Population-based Survey for Improving Consumer Safety (HK$346,340)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Kim Jean Hee, School of Public Health and Primary Care

Anaesthesia-related Complications in Adult Passive Smokers (HK$919,020)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Anna Lee, Department of Anaesthesia and Intensive Care

Anthropometric and Physiological Measurements in Healthy Children (HK$466,652)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Timothy Hudson Rainer, Accident and Emergency Medicine Academic Unit

Beneficial Interaction between Chinese Medicine Marsdenia Tenacissima and Anti-cancer Drugs via Reversal of ABC Drug Transporter-mediated Multidrug Resistance (HK$983,280)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Lin Ge, School of Biomedical Sciences

Diagnosis of Chromosomal Abnormalities: The Application and Use of Microarray Technology in the Hong Kong Health Service (HK$849,840)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Choy Kwong-wai Richard, Department of Obstetrics and Gynaecology

Effect of Hong Kong’s Ban on Smoking in Public Places on Incidence of Acute Myocardial Infarction (HK$62,070)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. William Bernard Goggins, School of Public Health and Primary Care

Embryotoxicity Studies of Rhizoma Atractylodis Macrocephalae Extracts for Skeletal Malformation in Mice (HK$1,000,000)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Wang Chi-chiu Ronald, Department of Obstetrics and Gynaecology

Familial Aggregation of Insomnia in Hong Kong Chinese: A Prospective, Case Control Study (HK$950,320)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Wing Yun-kwok, Department of Psychiatry

Normal Reference Values of Twenty-four-hour Ambulatory Blood Pressure Monitoring in Healthy School-aged Children and Adolescents in Hong Kong (HK$847,596)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Yip Wai-kwok Gabriel, Department of Medicine and Therapeutics

Poststroke Aggression among Hong Kong Stroke Survivors (HK$999,660)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Tang Wai-kwong, Department of Psychiatry

The Impact of Fast-track Perioperative Programme on the Clinical and Immunological Outcomes after Laparoscopic Colorectal Surgery in Hong Kong Chinese Patients: A Prospective Randomized Trial (HK$891,520)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Ng Siu-man Simon, Department of Surgery

Validation of Selective Attention and Memory Measures as Early Markers for Alzheimer’s Disease in Hong Kong (HK$832,105)
Sponsor: Health and Health Services Research Fund
Principal investigator: Prof. Tse Chi-shing, Department of Educational Psychology

Xiqu Information Centre 2010–11 (HK$500,000)
Sponsor: Hong Kong Arts Development Council
Principal investigator: Prof. Tsai Tsan-huang, Cantonese Opera Research Programme

A Bio-activity Guided in Vitro Pharmacokinetic Method to Improve the Quality Control of Chinese Medicines — Part 2 (Achieving Greater Relevance) (HK$930,000)
Sponsor: Innovation and Technology Fund — Innovation and Technology Support Programme
Principal investigator: Prof. Zuo Zhong, School of Pharmacy

Development of a Vitamin-C Surgical Irrigation Solution to Improve Healing Outcomes of Surgical Repair of Tendon and Ligament Injuries (HK$549,309)
Sponsor: Innovation and Technology Fund — Innovation and Technology Support Programme
Principal investigator: Prof. Chan Kai-ming, Department of Orthopaedics and Traumatology

High-efficiency SIMO Power Converter for SoC (HK$991,093)
Sponsor: Innovation and Technology Fund — Innovation and Technology Support Programme
Principal investigator: Prof. Leung Ka-nang Alex, Department of Electronic Engineering

Hybrid Actuation Mechanism for Active Wireless Capsule Endoscope (HK$998,200)
Sponsor: Innovation and Technology Fund — Innovation and Technology Support Programme
Principal investigator: Prof. Meng Qing-hu Max, Department of Electronic Engineering

Intelligent Video Revampment and Upsampling (HK$999,964)
Sponsor: Innovation and Technology Fund — Innovation and Technology Support Programme
Principal investigator: Prof. Jia Jiaya, Department of Computer Science and Engineering

Efficacy of Reversine as a Potent Inhibitor of Liver Fibrosis (HK$1,988,495)
Sponsor: Innovation and Technology Fund — University-Industry Collaboration Programme — Matching Grant for Joint Research Scheme and Zhang Long Industrial Company Limited
Principal investigator: Prof. Lee Ka-ho Kenneth, School of Biomedical Sciences

Jacobs Foundation — Parenting Across Cultures Study (USD20,100)
Sponsor: Jacobs Foundation — Klaus J. Jacobs Research Prize
Principal investigator: Prof. Chang Lei, Department of Educational Psychology

Nursing Workshop on Comprehensive Management of Bladder Dysfunction (HK$43,000)
Sponsor: Professional Services Development Assistance Scheme
Principal investigator: Prof. Yip Kam-hung Sidney, Department of Surgery

Game-based Collaborative Inquiry Learning between Hong Kong and Beijing Primary Schools (HK$599,000)
Sponsor: Quality Education Fund
Principal investigator: Dr. Jong Siu-yung Morris, Centre for the Advancement of Information Technology in Education

I am my Body — Healthy Life and Life Education in the Context of Embodiment (Stage 1) (HK$520,400)
Sponsor: Quality Education Fund
Principal investigator: Prof. Kung Lap-yan, Department of Cultural and Religious Studies

Quality Education Fund Thematic Network Healthy Schools (2010–11) (HK$1,503,910)
Sponsor: Quality Education Fund
Principal investigator: Prof. Albert Lee, Centre for Health Education and Health Promotion

Virtual Trainer: An Innovated Approach for Promoting Active Lifestyle, Health and Fitness of Secondary School Students (HK$502,300)
Sponsor: Quality Education Fund
Principal investigator: Prof. Hui Sai-chuen Stanley, Department of Sports Science and Physical Education

Bacteria-derived DNA Fragment in Peritoneal Dialysis Effluent as a Predictor of Relapsing Peritonitis (HK$751,280)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Szeto Cheuk-chun, Department of Medicine and Therapeutics

Characterization of Sequence Variation of Human Papillomavirus 52 Circulating in Hong Kong and Worldwide for Establishment of Classification System and Identification of High-risk Mutations (HK$504,906)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Chan Kay-sheung Paul, Department of Microbiology

Clarification of the Role of H. Pylori Infection on Activation of STAT3 through Dissecting STAT3 Signaling Network in Gastric Cancer (HK$934,320)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Yu Jun, Institute of Digestive Disease

Development of a Peptide Ligand-based Technology for Selective Enrichment of Mycobacterium Tuberculosis in Sputum (HK$830,972)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Chan Chiu-yeung Raphael, Department of Microbiology

Development of Efficient Photosensitizing Systems for Antimicrobial Photodynamic Therapy Against Multidrug-Resistant Microbial Pathogens (HK$961,774)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Lo Pui-chi, Department of Chemistry

Effect of Scutellariae Radix (Huangqin) and Its Major Flavonoids on Preventing Rhinovirus — Provoked Asthmatic Inflammation in a Cell Model of Cultured Human Bronchial Epithelia (HK$80,000)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Ko Wing-hung, School of Biomedical Sciences

Functional Profiling and Strategic Antimicrobial Manipulation of a Universal Nutrition-sensing Network that Regulates Microbial Virulence, Antibiotic Tolerance and Stress Protection (HK$972,472)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Dr. Chan Wai-chi Edward, Department of Microbiology

Human Epigenetic Alterations in Mycobacterium Tuberculosis Infection — A Novel Platform to Eavesdrop Interactions between MTB and Host Immunity (HK$1,000,000)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Dr. Leung Tung-yiu Eric, Department of Microbiology

Identification of Circulating Antigens in Patients with Helicobacter Pylori Infection (HK$978,648)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Poon Chuen-wai Terence, Department of Paediatrics

Identification of Pathogenic microRNA in Helicobacter Pylori-associated Gastric Cancer Using a Combined Approach of Animal Study and Clinical Sample Analysis (HK$999,040)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Cho Chi-hin, School of Biomedical Sciences

Mechanisms of Antifungal Action of a Bean Defensin Lactoferrin and Lactoferrin-derived Peptides on Planktonic Candida Albicans (HK$939,654)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Ng Tzi-bun, School of Biomedical Sciences

Mechanistic Studies on Bakuchiol and Macrocarpal C with Regards to Their Anti-dermatophyte Effects in Vitro and Tinea Pedis-Treating Activities in Vivo (HK$999,280)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Lau Bik-san Clara, Institute of Chinese Medicine

Modified Maize Ribosome-inactivating Protein as a Possible Anti-HIV Agent by the SIV-infected Rhesus Macaque Model (HK$999,240)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Shaw Pang-chui, School of Life Sciences

Screening of Aqueous and Organic Extracts of a Variety of Fungi for the Ability to Antagonize the Pathogenic Yeast Candida Albicans (HK$80,000)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Ng Tzi-bun, School of Biomedical Sciences

Search of Inhibitors that Target HIV Pre-mRNA Splicing to Overcome Drug Resistance (HK$998,520)
Sponsor: Research Fund for the Control of Infectious Diseases
Principal investigator: Prof. Ngo Chi-ki, School of Life Sciences